Effects of curcumin therapy in Alzheimer disease

Posted on May 14, 2012 by MDR

Curcumin, the phytochemical agent in the spice turmeric, which gives Indian curry its yellow colour, is also a traditional Indian medicine. The antioxidant, anti-inflammatory, antiproliferative and other properties of curcumin have only recently gained the attention of modern pharmacology. Over the past decade, research with curcumin has increased significantly. In vitro and in vivo studies have demonstrated that curcumin could target pathways involved in the development of Alzheimer disease (AD), such as the β-amyloid cascade, tau phosphorylation, neuroinflammation or oxidative stress. These findings suggest that curcumin might be a promising compound for the development of AD therapy. However, its insolubility in water and poor bioavailability have limited clinical trials and its therapeutic applications. To be effective as a drug therapy, curcumin must be combined with other drugs, or new delivery strategies need to be developed. http://www.ncbi.nlm.nih.gov/pubmed/22051121

Posted in Brain Health/Memory | Leave a comment

Sleeping less makes you eat more!

Posted on April 17, 2012 by MDR

Evidence shows an increase in obesity is related to a reduction in average sleep duration among Americans. Although clinical studies propose that restricted sleep affects hormones related to appetite, neuronal activity in response to food stimuli after restricted and habitual sleep has not been investigated. In this study, thirty healthy, normal-weight [BMI (in kg/m2): 22–26] men and women were recruited (26 completed) to participate in a 2-phase inpatient crossover study in which they spent either 4 h/night (restricted sleep) or 9 h/night (habitual sleep) in bed. Each phase lasted 6 days. Results showed that response to food stimuli was greater after restricted sleep than after habitual sleep. In addition, a relative increase in brain activity in areas associated with reward, in response to food stimuli, was observed. http://www.ajcn.org/content/95/4/818.abstract

Posted in Uncategorized, Weight Loss/Fitness | Leave a comment

Lower blood pressure naturally, with magnesium!

Posted on April 2, 2012 by MDR

blood pressure, lower blood pressureResearchers from the University of Hertfordshire have found that magnesium supplements may offer small but clinically significant reductions in blood pressure. In an study published in the European Journal of Clinical Nutrition, the researchers also discovered that the size of the effect increased in line with increased dosage. Up until now, evidence that magnesium helps lower blood pressure has been unconfirmed. In these new trials, magnesium supplementation doses ranged from 120 to 973 mg with between 3 to 24 weeks of follow-up. While not all individual trials showed significance in blood pressure reduction, by combining the trials, the overall data indicated that magnesium supplementation reduced both systolic and diastolic blood pressure. With the best results observed at the higher dosages.

http://www.nature.com/ejcn/journal/vaop/ncurrent/full/ejcn20124a.html

Posted in Cardiovascular Health, Uncategorized | Tagged , , | Leave a comment

Lutein offers protection against macular degeneration

Posted on March 22, 2012 by MDR

Lutein and zeaxanthin are thought to decrease the incidence of age-related macular degeneration (AMD). This reviews shows that dietary intake of these carotenoids was significantly related with a reduction in risk of late AMD and a statistically significant inverse association was observed between lutein and zeaxanthin intake and neovascular AMD risk. The findings of the present meta-analysis indicate that dietary lutein and zeaxanthin is not significantly associated with a reduced risk of early AMD, whereas an increase in the intake of these carotenoids may be protective against late AMD.

http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8479176&fulltextType=RV&fileId=S0007114511004260

Related product:
Vision Formula with 10 mgs of Lutein.
Formulated to specifically support healthy vision. In addition to lutein, also included in the formula are Grape Seed Extract, Green Tea Extract, Bilberry, and Lycopene – ingredients rich in antioxidants that help support healthy blood vessels and lens integrity. HTTP://WWW.MDR.COM

 

Posted in Vision Health | Leave a comment

Effects of curcumin therapy in Alzheimer disease

Posted on March 22, 2012 by MDR

Curcumin, the phytochemical agent in the spice turmeric, which gives Indian curry its yellow colour, is also a traditional Indian medicine. The antioxidant, anti-inflammatory, antiproliferative and other properties of curcumin have only recently gained the attention of modern pharmacology. Over the past decade, research with curcumin has increased significantly. In vitro and in vivo studies have demonstrated that curcumin could target pathways involved in the development of Alzheimer disease (AD), such as the β-amyloid cascade, tau phosphorylation, neuroinflammation or oxidative stress. These findings suggest that curcumin might be a promising compound for the development of AD therapy. However, its insolubility in water and poor bioavailability have limited clinical trials and its therapeutic applications. To be effective as a drug therapy, curcumin must be combined with other drugs, or new delivery strategies need to be developed.

http://www.ncbi.nlm.nih.gov/pubmed/22051121

Posted in Brain Health/Memory | Leave a comment

Why you should drink red wine with red meat

Posted on February 23, 2012 by MDR

For years, medical experts have been telling us to go easy on red meat since the fat it contains releases toxic substances when digested. Well, meat lovers – here’s good news. Do what the French do. Have a glass of red wine with your meat. Why? Researchers discovered that when red wine combines with red meat, it reduces the formation of those toxic chemicals. The polyphenols in the red wine (powerful antioxidants) also help prevent the absorption of the toxic compounds from the gastrointestinal tract into the blood stream.

http://pubs.acs.org/doi/abs/10.1021/jf703700d

MDR makes an excellent supplement that contains the polyphenol resveratrol. Check it out at:

http://www.mdr.com/Ultra-Pure-Resveratrol-60-softgels/productinfo/310330/

Posted in Cardiovascular Health | Leave a comment

A special form of vitamin E may keep us young!

Posted on February 6, 2012 by MDR

Recapture your youth with tocotrienols

A powerful form of vitamin E, called tocotrienols, has been shown to prevent cellular aging. As we age, telomeres shorten with decreased telomerase activity and levels of damaged DNA increase. Telomeres reside at either of the sections of DNA occurring at the ends of a chromosome. Telomeres protect the DNA material inside the chromosomes. The shortening of telomeres during each round of cell division may be part of the natural aging of cells. Researchers reversed the aging of older cells to resemble that of young cells by decreasing damaged DNA and telomere length.
http://www.ncbi.nlm.nih.gov/pubmed/21541185

Posted in Anti-Aging/Longevity | Leave a comment

Folic acid and B12 improves memory in older folks

Posted on January 17, 2012 by MDR

A randomized controlled trial comprising daily oral 400 μg folic acid + 100 μg vitamin B-12 supplementation (compared with placebo) was taken by participants for 2 years to observe if the vitamins made a difference in their memory. Results showed that long-term supplementation of daily oral 400 μg FA + 100 μg vitamin B-12 promotes improvement in cognitive functioning after 24 mo, particularly in immediate and delayed memory performance.

http://www.ajcn.org/content/95/1/194.abstract

MDR’s Vitamin B-12 Liquid Complex is a berry-flavored tasty liquid that provides you with an easy way to get a “shot” of the entire B complex you need for overall health and well-being. Once or twice a week, place a full dropper of Vitamin B-12 Liquid Complex under your tongue, wait 30 seconds, then swallow your way to a healthier day.

Posted in Uncategorized | Leave a comment

Low vitamin D may increase stroke & heart attack risk in women

Posted on December 1, 2011 by MDR

Preliminary data just revealed that postmenopausal white women aged 45 to 58 with a vitamin D deficiency had more risk factors for heart disease than women with normal levels of the vitamin. Women with low vitamin D levels had higher levels of triglycerides; higher fasting glucose; a higher body mass index; and lower HDL “good” cholesterol. The researchers noted 47 percent of the women who were deficient in vitamin D were smokers compared to 38 percent of the women with normal vitamin D levels. About 15 percent of the women deficient in vitamin D either died or suffered heart failure, a heart attack or stroke during the study period compared to 10.2 percent of the women who did not have this deficiency. Another study found that higher levels of vitamin D were associated with lower death rates from cardiovascular disease.
www.nlm.nih.gov/medlineplus/news/fullstory_118730.html
Look into MDR.com for our calcium and vitamin D product – Day-Cal and Nite-Cal

Posted in Cardiovascular Health | Leave a comment

Cancer chemoprevention by pomegranate

Posted on November 8, 2011 by MDR

Pomegranate fruit is rich in antioxidant tannins and flavonoids, which is believed to have exceptional healing qualities. Recent research has shown that pomegranate extracts inhibit the growth of breast, prostate, colon and lung cancer cells in culture. In preclinical animal studies, oral consumption of pomegranate extract inhibited growth of lung, skin, colon and prostate tumors. An initial phase II clinical trial of pomegranate juice in patients with prostate cancer reported significant prolongation of prostate specific antigen doubling time. http://www.ncbi.nlm.nih.gov/pubmed/20155621

Posted in Cell Health | Leave a comment